Michael’s practice area is intellectual property, especially in the fields of biotechnology, chemistry, bioinformatics, pharmaceuticals and medical devices. He works directly with inventors and in-house counsel to draft and prosecute patent applications and engages in the preparation of patentability, validity and related opinions. He handles product clearance searches, product evaluations, inventorship analysis, non-disclosure agreements and licensing agreements. Michael also performs due diligence in connection with mergers and acquisitions in the biotechnology and pharmaceutical industries.
Since 2001, Michael has practiced before the U.S. Patent and Trademark Office. He was an assistant professor of biochemistry and molecular biology at The George Washington University and the Children’s National Medical Center from 1997 to 2002. His research experience includes:
Development of adenoviral and AAV vectors and delivery methods for gene therapy
In utero gene transfer and induction of cellular and humeral immune tolerance by prenatal and neonatal immunization
Evaluation of immune responses and pharmacokinetics of therapeutic gene expression following viral administration
Development of inducible expression systems for controlled transgene expression
Evaluation of autoimmune responses to tumor antigens
Signal transduction mechanism and vaccine development
Articles in the National Law Review database by Michael Xuehai Ye, Ph.D.