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INRS 2016/2017 Brochure Includes Studies in Progress Concerning Manufactured Nanomaterials

On November 23, 2017, the French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases (INRS) published a report summarizing studies and research completed in 2016 and in progress in 2017.  According to the report, INRS action on manufactured nanomaterials has three objectives:  (1) making knowledge on hazards available to the working world; (2) designing tools for identifying, characterizing, and measuring occupational exposures; and (3) proposing risk prevention approaches and tools for firms and laboratories that produce or handle these materials.  In 2016, INRS completed a study entitled “Impact of sources and of the environment on confinement of nanoparticulate pollutants by collective protective equipment.”  The objective of the study was to develop the tools necessary for assessing the effectiveness of collective protection systems, based on ventilation, for protecting people from nanoparticle aerosols.  Three focuses for action were identified:  characterizing the sources of nanoparticle aerosols; studying the airflow factors in degradation of the confinement of ventilated enclosures; and developing models for numerically simulating the dispersion of nanoaerosols at workplaces (predictive ventilation).  According to INRS, the results made it possible to identify the main nanomaterial aerosol sources present in ventilated enclosures.  An experimental method of characterizing the generation flow rates of these sources that is applicable out in the field was then developed and validated.  A realistic predictive model for the variation in pollutant nanoaerosols in work atmospheres was designed.

Studies in progress in 2017 include:

  • Study of the effect of agglomeration on the respiratory toxicological properties and the toxicokinetics of inhaled titanium dioxide nanoparticles in rats (2013-2017);

  • Study of neuro-inflammation and of potential disruptions of the blood-brain barrier in adult and old rats exposed to nanoparticulate titanium dioxide by inhalation (2014-2017);

  • A common European approach for regulatory assessment of nanomaterials (NANOREG) (2013-2017);

  • Development of a smart experimental approach for assessing the hazard related to nanomaterials (European project SMARTNANOTOX) (2016-2020);

  • Performance of real-time exposure monitoring applied to nanoparticle aerosols (2014-2018);

  • Multiparametric characterization of metal ultrafine particles (2016-2019);

  • Optimizing methods of sampling ultrafine particles of metal aerosols using cascade impactors (2016-2020);

  • Assessment of exposure to nanometric titanium dioxide (2014-2017);

  • Standardization of activities concerning nanotechnologies and nanomaterials (NANOCEN) (2013-2018);

  • EXPROPNANO: Assessment of occupational exposure to nanometric particles (measurement strategy coupled with analysis of the activity) (2015-2017);

  • Nanomaterials and occupational exposure during operations implementing powders: study of the relationships between the physico-chemical properties of the powders and the characteristics of the aerosols emitted at workplaces (2016-2019); and

  • Performance of filtering and isolating respiratory protective devices in protecting from nanoparticles (2013-2017).

©2020 Bergeson & Campbell, P.C.National Law Review, Volume VII, Number 343
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Lynn Bergeson, Campbell PC, Toxic Substances Control Act Attorney, federal insecticide lawyer, industrial biotechnology legal counsel, Food Drug Administration law
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Lynn L. Bergeson has earned an international reputation for her deep and expansive understanding of the Toxic Substances Control Act (TSCA), the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), European Union Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), and especially how these regulatory programs pertain to nanotechnology, industrial biotechnology, synthetic biology, and other emerging transformative technologies. Her knowledge of and involvement in the policy process allows her to develop client-focused strategies whether...

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Carla Hutton, Bergeson Campbell PC, global regulatory attorney, public health activists lawyer, metals industry legal counsel, Toxic Substances Control Act law
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Since 1996, Carla Hutton has monitored, researched, and written about regulatory and legislative issues that may potentially affect Bergeson & Campbell, P.C. (B&C®) clients. She is responsible for creating a number of monthly and quarterly regulatory updates for B&C's clients, as well as other documents, such as chemical-specific global assessments of regulatory developments and trends. She authors memoranda for B&C clients on regulatory and legislative developments, providing information that is focused, timely and applicable to client initiatives. These tasks have proven invaluable to many clients, keeping them aware and abreast of developing issues so that they can respond in kind and prepare for the future of their business.

Ms. Hutton brings a wealth of experience and judgment to her work in federal, state, and international chemical regulatory and legislative issues, including green chemistry, nanotechnology, the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the Toxic Substances Control Act (TSCA), Proposition 65, and the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) program.

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