ASTM recently announced that it published a standard, E3275, that seeks to familiarize laboratory scientists with background information and technical content necessary to image and identify engineered nanomaterials in cellular and noncellular samples. According to ASTM, the standard is specific to the use of the darkfield microscopy/hyperspectral imaging analysis technique. ASTM states that in this technique, the resulting sample analysis allows for direct visualization and identification of the nanomaterials based on comparison to the spectral profiles of well-characterized reference nanomaterials.