iThe U.S. Environmental Protection Agency (EPA) published a Federal Register notice on April 28, 2021, announcing a 30-day comment period on the Toxic Substances Control Act (TSCA) Interagency Testing Committee’s (ITC) revisions to the Priority Testing List. 86 Fed. Reg. 22414. In the 74th ITC Report, ITC revised the TSCA Section 4(e) Priority Testing List by adding the following 15 high-priority substances designated pursuant to TSCA Section 6(b) and 24 organohalogen flame retardants:
| Chemical Substance | Chemical Abstracts Service Registry Number |
| High-Priority Substances | |
| 1,3-Butadiene | 106-99-0 |
| Butyl benzyl phthalate (BBP) - 1,2-Benzene- dicarboxylic acid, 1- butyl 2(phenylmethyl) ester | 85-68-7 |
| Dibutyl phthalate (DBP) (1,2-Benzene- dicarboxylic acid, 1,2- dibutyl ester) | 84-74-2 |
| o-Dichlorobenzene | 95-50-1 |
| p-Dichlorobenzene | 106-46-7 |
| trans-1,2- Dichloroethylene | 156-60-5 |
| 1,2-Dichloropropane | 78-87-5 |
| Dicyclohexyl phthalate | 84-61-7 |
| Di-ethylhexyl phthalate (DEHP) - (1,2-Benzene- dicarboxylic acid, 1,2- bis(2- ethylhexyl) ester) | 117-81-7 |
| Di-isobutyl phthalate (DIBP) - (1,2-Benzene- dicarboxylic acid, 1,2- bis-(2methylpropyl) ester) | 84-69-5 |
| Formaldehyde | 50-00-0 |
| 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta [g]-2-benzopyran (HHCB) | 1222-05-5 |
| Phthalic anhydride | 85-44-9 |
| 4,4'-(1-Methylethylidene)bis[2, 6-dibromophenol] (TBBPA) | 79-94-7 |
| 1,1,2-Trichloroethane | 79-00-5 |
| Organohalogen Flame Retardants | |
| Bis(hexachlorocyclopentadieno)cyclooctane | 13560-89-9 |
| 1,2-Bis(2,4,6-tribromophenoxy)ethane | 37853-59-1 |
| 1,1'-Ethane-1,2-diylbis(pentabromobenzene) | 84852-53-9 |
| 2-(2-Hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate | 20566-35-2 |
| 2,2'-[(1-Methylethylidene)bis[(2,6-dibromo-4,1- phenylene)oxymethylene]]bis[oxirane] |
3072-84-2 |
| Mixture of chlorinated linear alkanes C14-17 with 45-52 % chlorine | 85535-85-9 |
| N,N-Ethylene-bis(tetrabromophthalimide) | 32588-76-4 |
| Pentabromochlorocyclohexane | 87-84-3 |
| (Pentabromophenyl)methyl acrylate | 59447-55-1 |
| Pentabromotoluene | 87-83-2 |
| Perbromo-1,4-diphenoxybenzene | 58965-66-5 |
| Phosphonic acid, (2-chloroethyl)-, bis(2-chloroethyl) ester | 6294-34-4 |
| Propanoic acid, 2-bromo-, methyl ester | 5445-17-0 |
| Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) | 21850-44-2 |
| Tetrabromobisphenol A bis(2-hydroxyethyl) ether | 4162-45-2 |
| Tetrabromobisphenol A diallyl ether | 25327-89-3 |
| Tetrabromobisphenol A dimethyl ether | 37853-61-5 |
| 2,4,6-Tribromoaniline | 147-82-0 |
| 1,3,5-Tribromo-2-(prop-2-en-1-yloxy)benzene | 3278-89-5 |
| Tris(2-chloroethyl) phosphite | 140-08-9 |
| Tris(2,3-dibromopropyl) phosphate | 126-72-7 |
| 1,3,5-Tris(2,3-dibromopropyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione | 52434-90-9 |
| Tris(tribromoneopentyl)phosphate | 19186-97-1 |
| 2,4,6-Tris-(2,4,6-tribromophenoxy)-1,3,5-triazine | 25713-60-4 |
ITC requests that EPA add these chemical substances and the other five high-priority substances and six organohalogen flame retardants currently on the Priority Testing List to 40 C.F.R. Section 716.120(a), the list of substances subject to the TSCA Section 8(d) Health and Safety Data Reporting rule (40 C.F.R. Part 716). The rule requires manufacturers (including importers) of chemical substances and mixtures added to the Health and Safety Data Reporting rule to submit lists and copies of unpublished health and safety studies to EPA. Comments are due May 28, 2021.
EPA notes that in addition to the chemical substances being added to the Priority Testing List in the 74th ITC Report, the Priority Testing List includes two alkylphenols, 45 High Production Volume (HPV) Challenge Program orphan chemicals, cadmium, a category of cadmium compounds, six non-phthalate plasticizers, 25 phosphate ester flame retardants, two other flame retardants, nine chemicals to which children living near hazardous waste sites may be exposed, and 19 diisocyanates and related compounds.
