EPA Seeks Nominations for Technical Experts to Review New Chemicals Collaborative Research Program
Friday, May 27, 2022

On May 27, 2022, the U.S. Environmental Protection Agency (EPA) requested nominations for technical experts to serve as special government employees (SGE) to participate in the review of the New Chemicals Collaborative Research Program with the Board of Scientific Counselors (BOSC), a federal advisory committee to EPA’s Office of Research and Development (ORD). 87 Fed. Reg. 32161. BOSC will be evaluating ORD’s draft Strategic Research Action Plans Fiscal Years 2023-2026 in fall 2022. According to EPA, the fall 2022 meeting will provide a more in-depth evaluation of the Toxic Substances Control Act (TSCA) New Chemicals Collaborative Research Program and associated research plan. EPA states that it will provide an additional draft document that summarizes technical details of the research plan. ORD, in partnership with the Office of Chemical Safety and Pollution Prevention (OCSPP), proposes to develop and implement a multi-year collaborative research program focused on approaches for performing risk assessments on new chemical substances under TSCA.

EPA will consider nominees from industry, business, public and private research institutes or organizations, academia, government (federal, state, local, and Tribal), non-governmental organizations, and other relevant interest areas. EPA notes that it values and welcomes diversity. EPA encourages all qualified candidates to apply regardless of gender, race, disability, or ethnicity.

EPA invites nominations of individuals to serve as SGEs with expertise or extensive experience in the following scientific disciplines and topic areas as they relate to human health and the environment:

  • Using data to develop predictive models and use of predictive models in data-poor environments:

    • Read across and analogue selection;

    • Chemical structures and cheminformatics; and

    • Quantitative structure-activity relationships (QSAR);

  • Development, implementation, and validation of new approach methods (NAM). Relevant expertise may include:

    • Veterinary pathology or comparative physiology for perspective on relevance of laboratory animals for predicting human outcomes; and

    • Reference data curation to support validation;

  • Computational modeling, bioinformatics, and/or statistics;

  • Toxicokinetics, physiologically based pharmacokinetic models (PBPK), and in vitro to in vivo extrapolation (IVIVE);

  • Systems biology;

  • Human health and ecological risk assessment;

  • Exposure modeling and/or assessment, including near-field and far-field sources;

  • Knowledge of TSCA; and

  • Environmental fate of chemicals.

Nominations are due June 30, 2022. More information on EPA’s Draft Document on “Modernizing the Process and Bringing Innovative Science to Evaluate New Chemicals Under TSCA” is available in our March 14, 2022, memorandum.

 

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