iThe U.S. Environmental Protection Agency (EPA) published a final rule on June 29, 2021, that requires manufacturers (including importers) of 50 specified chemical substances to report certain lists and copies of unpublished health and safety studies to EPA. 86 Fed. Reg. 34147. EPA is issuing the final rule pursuant to Section 8(d) of the Toxic Substances Control Act (TSCA) and the TSCA Health and Safety Data Reporting rule codified at 40 C.F.R. Part 716. The chemical substances subject to the rule consist of the 20 designated by EPA as high-priority substances and the 30 organohalogen flame retardants being evaluated for risks by the Consumer Product Safety Commission (CPSC) under the Federal Hazardous Substances Act (FHSA). EPA states that it is taking this action because the TSCA Interagency Testing Committee (ITC) added these chemical substances to the TSCA Section 4(e) Priority Testing List through its 69th and 74th Reports. EPA will use the submitted information to inform the risk evaluations currently underway for 20 high-priority substances and for future prioritization.
The final rule will be effective July 29, 2021. Requests to withdraw a chemical substance from the final rule pursuant to 40 C.F.R. Section 716.105(c) must be received by July 13, 2021. Information specified in the final rule is due to EPA by September 27, 2021. Detailed information about the final rule is available in our June 29, 2021, memorandum, “Manufacturers and Importers of 20 High-Priority Chemicals and 30 Organohalogen Flame Retardants Must Submit Data to EPA.”
The table below lists the high-priority substances and organohalogen flame retardants included in the final rule.
| Chemical Substance | Chemical Abstracts Service Registry Number |
| High-Priority Substances | |
| 1,3-Butadiene | 106-99-0 |
| Butyl benzyl phthalate (BBP) (1,2-Benzene-dicarboxylic acid, 1-butyl 2-(phenylmethyl) ester) | 85-68-7 |
| Dibutyl phthalate (DBP) (1,2-Benzene-dicarboxylic acid, 1,2-dibutyl ester) | 84-74-2 |
| o-Dichlorobenzene | 95-50-1 |
| p-Dichlorobenzene | 106-46-7 |
| 1,1-Dichloroethane | 75-34-3 |
| 1,2-Dichloroethane | 107-06-2 |
| trans-1,2-Dichloroethylene | 156-60-5 |
| 1,2-Dichloropropane | 78-87-5 |
| Dicyclohexyl phthalate | 84-61-7 |
| Di-ethylhexyl phthalate (DEHP) (1,2-Benzene-dicarboxylic acid, 1,2-bis(2-ethylhexyl) ester) | 117-81-7 |
| Di-isobutyl phthalate (DIBP) (1,2-Benzene-dicarboxylic acid, 1,2-bis(2-methylpropyl) ester) | 84-69-5 |
| Ethylene dibromide | 106-93-4 |
| Formaldehyde | 50-00-0 |
| 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (HHCB) | 1222-05-5 |
| 4,4'-(1-Methylethylidene)bis[2,6-dibromophenol] (TBBPA) | 79-94-7 |
| Phosphoric acid, triphenyl ester (TPP) | 115-86-6 |
| Phthalic anhydride | 85-44-9 |
| 1,1,2-Trichloroethane | 79-00-5 |
| Tris(2-chloroethyl) phosphate (TCEP) | 115-96-8 |
| Organohalogen Flame Retardants | |
| Bis(2-ethylhexyl) tetrabromophthalate | 26040-51-7 |
| Bis(hexachlorocyclopentadieno)cyclooctane | 13560-89-9 |
| 1,2-Bis(2,4,6-tribromophenoxy)ethane | 37853-59-1 |
| 1,1'-Ethane-1,2-diylbis(pentabromobenzene) | 84852-53-9 |
| 2-Ethylhexyl-2,3,4,5-tetrabromobenzoate | 183658-27-7 |
| 2-(2-Hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate | 20566-35-2 |
| 2,2'-[(1-Methylethylidene)bis[(2,6-dibromo-4,1-phenylene)oxymethylene]]bis[oxirane] | 3072-84-2 |
| Mixture of chlorinated linear alkanes C14-17 with 45-52 % chlorine | 85535-85-9 |
| N,N-Ethylene-bis(tetrabromophthalimide) | 32588-76-4 |
| Pentabromochlorocyclohexane | 87-84-3 |
| (Pentabromophenyl)methyl acrylate | 59447-55-1 |
| Pentabromotoluene | 87-83-2 |
| Perbromo-1,4-diphenoxybenzene | 58965-66-5 |
| Phosphonic acid, (2-chloroethyl)-, bis(2-chloroethyl) ester | 6294-34-4 |
| Phosphoric acid, 2,2-bis(chloromethyl)-1,3-propanediyl tetrakis(2-chloroethyl) ester | 38051-10-4 |
| Propanoic acid, 2-bromo-, methyl ester | 5445-17-0 |
| Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) | 21850-44-2 |
| Tetrabromobisphenol A bis(2-hydroxyethyl) ether | 4162-45-2 |
| Tetrabromobisphenol A diallyl ether | 25327-89-3 |
| Tetrabromobisphenol A dimethyl ether | 37853-61-5 |
| 2,4,6-Tribromoaniline | 147-82-0 |
| 1,3,5-Tribromo-2-(prop-2-en-1-yloxy)benzene | 3278-89-5 |
| Tris(2-chloroethyl)phosphite | 140-08-9 |
| Tris(1-chloro-2-propyl)phosphate | 13674-84-5 |
| Tris(2-chloro-1-propyl)phosphate | 6145-73-9 |
| Tris(2,3-dibromopropyl)phosphate | 126-72-7 |
| 1,3,5-Tris(2,3-dibromopropyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione | 52434-90-9 |
| Tris(1,3-dichloro-2-propyl)phosphate | 13674-87-8 |
| Tris(tribromoneopentyl)phosphate | 19186-97-1 |
| 2,4,6-Tris-(2,4,6-tribromophenoxy)-1,3,5-triazine | 25713-60-4 |
