September 28, 2020

Volume X, Number 272

September 28, 2020

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ISO Standard Specifies Method for Testing Photocatalytic Activity of Nanoparticles for NADH Oxidation

The International Organization for Standardization (ISO) has published standard ISO 20814:2019, “Nanotechnologies — Testing the photocatalytic activity of nanoparticles for NADH oxidation.”  The standard specifies a method for the measurement of the photocatalytic activity (PCA) of nanoparticles (NP), suspended in an aqueous environment in physiologically relevant conditions, by measuring the ultraviolet (UV)-induced nicotine adenine dinucleotide hydrate (NADH) oxidation.  According to ISO, the measurement is intended to assess the potential for the photo-toxicity of nanomaterials.  The method is also applicable to NP aggregates and agglomerates.  ISO states that existing standard test methods for particle and surface PCA measurement (see ISO 10676 and ISO 10678) are not directly applicable to determine nanomaterial PCA leading to photo-toxicity, as they require a large test volume and/or long measurement duration, while using organic dyes as indicators that are not biocompatible.

©2020 Bergeson & Campbell, P.C.National Law Review, Volume IX, Number 345

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Lynn Bergeson, Campbell PC, Toxic Substances Control Act Attorney, federal insecticide lawyer, industrial biotechnology legal counsel, Food Drug Administration law
Managing Partner

Lynn L. Bergeson has earned an international reputation for her deep and expansive understanding of the Toxic Substances Control Act (TSCA), the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), European Union Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), and especially how these regulatory programs pertain to nanotechnology, industrial biotechnology, synthetic biology, and other emerging transformative technologies. Her knowledge of and involvement in the policy process allows her to develop client-focused strategies whether...

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Carla Hutton, Bergeson Campbell PC, global regulatory attorney, public health activists lawyer, metals industry legal counsel, Toxic Substances Control Act law
Regulatory Analyst

Since 1996, Carla Hutton has monitored, researched, and written about regulatory and legislative issues that may potentially affect Bergeson & Campbell, P.C. (B&C®) clients. She is responsible for creating a number of monthly and quarterly regulatory updates for B&C's clients, as well as other documents, such as chemical-specific global assessments of regulatory developments and trends. She authors memoranda for B&C clients on regulatory and legislative developments, providing information that is focused, timely and applicable to client initiatives. These tasks have proven invaluable to many clients, keeping them aware and abreast of developing issues so that they can respond in kind and prepare for the future of their business.

Ms. Hutton brings a wealth of experience and judgment to her work in federal, state, and international chemical regulatory and legislative issues, including green chemistry, nanotechnology, the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the Toxic Substances Control Act (TSCA), Proposition 65, and the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) program.

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